• Users Online: 212
  • Home
  • Print this page
  • Email this page
Home Current issue Ahead of print Search About us Editorial board Archives Submit article Instructions Subscribe Contacts Login 
ORIGINAL ARTICLE
Year : 2018  |  Volume : 111  |  Issue : 1  |  Page : 7-14

Correlation of retinal nerve fiber layer thickness and perimetric changes in primary open-angle glaucoma


1 Department of Ophthalmology, Ministry of Health, Faculty of Medicine, Mansoura University, Mansoura, Egypt
2 Department of Ophthalmology, Mansoura Ophthalmic Center, Faculty of Medicine, Mansoura University, Mansoura, Egypt

Correspondence Address:
Hossam Y Abouelkheir
Department of Ophthalmology, Mansoura Ophthalmic Center, Faculty of Medicine, Mansoura University, Mansoura 35516
Egypt
Login to access the Email id

Source of Support: None, Conflict of Interest: None


DOI: 10.4103/ejos.ejos_5_18

Rights and Permissions

Purpose This study aims at evaluating the relation between retinal nerve fiber layer (RNFL) thickness evaluated by spectral-domain optical coherence tomography (OCT) in primary open-angle glaucoma and visual field sensitivity. Patients and methods A total of 20 normal and 60 glaucomatous eyes were included in this study. Glaucomatous eyes were graded into early, moderate and severe stages according to Hodapp, Parrish, and Anderson classification. Complete ophthalmic examination, white-on-white perimetry and spectral-domain OCT were done for all patients. RNFL thickness of quadrants and average thickness were recorded. Area under receiver operating characteristic curves were used to assess the performance of OCT parameters. Results Average RNFL thickness was the best parameter to discriminate normal from early glaucoma, early from moderate and moderate from severe. Average RNFL loss was 14.9% in early glaucoma, 25.1% in moderate glaucoma and 37.2% in severe glaucoma. A significant correlation was detected between mean deviation and average RNFL thickness. Conclusion The present study found that average RNFL thickness has a good diagnostic value for diagnosis of glaucoma and for differentiating between glaucoma stages according to its severity.


[FULL TEXT] [PDF]*
Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)
 

 Article Access Statistics
    Viewed65    
    Printed2    
    Emailed0    
    PDF Downloaded22    
    Comments [Add]    

Recommend this journal