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ORIGINAL ARTICLE
Year : 2017  |  Volume : 110  |  Issue : 4  |  Page : 110-113

Hydroxychloroquine retinopathy in a cohort of patients from upper Egypt


1 Department of Ophthalmology, Faculty of Medicine, Sohag University, Sohag, Egypt
2 Department of Rheumatology, Faculty of Medicine, Sohag University, Sohag, Egypt

Correspondence Address:
Mortada A Abozaid
Department of Ophthalmology, Faculty of Medicine, Sohag University, Sohag
Egypt
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/ejos.ejos_39_17

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Purpose To identify risk factors and state demographics of a cohort of patients from upper Egypt experiencing hydroxychloroquine (HCQ) retinopathy. This was an observational study. This study was conducted in Sohag University Hospital, Egypt. Patients and methods The medical records of the rheumatology department were retrospectively reviewed to identify patients who stopped taking HCQ owing to its induced visual troubles. Ten patients were identified and were subjected to complete ophthalmological examination in addition to automated perimetry and optical coherence tomography of the macula. Results All patients (nine females and one male) had received HCQ 200 mg twice daily for years. The mean age was 59.1 years, mean real weight was 83.3 kg, mean height was 1.63 m, mean ideal body weight was 56.72 kg, and the mean daily dose per kg of ideal weight was 7.14 mg/kg/day, whereas the mean daily dose per kg of real weight was 4.85 mg/kg/day. Conclusion Calculation of HCQ dose according to the ideal weight is a better predector of retinal toxicity than real body weight.


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