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ORIGINAL ARTICLE
Year : 2014  |  Volume : 107  |  Issue : 1  |  Page : 41-44

Transepithelial photorefractive keratectomy with adjunctive mitomycin-C for correction of residual myopia after LASIK


Department of Ophthalmology, Suez Canal University, Ismailia, Egypt

Correspondence Address:
Waleed A Ghobashy
MD, 6# Ibrahim Alkhalil Street, Doctors Land, Ring Road, 41511, +2064, Ismailia
Egypt
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/2090-0686.134949

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Purpose The aim of the study was to evaluate the efficacy and safety of transepithelial photorefractive keratectomy (trans-PRK) with adjunctive mitomycin-C (MMC) over laser in-situ keratomileusis (LASIK) flaps for the treatment of residual myopia following LASIK. Materials and methods In this single-center, retrospective clinical study, 12 eyes of nine patients (mean age 32.67 ± 2.8 years) who were administered MMC (0.02%, 20 s) during trans-PRK for the treatment of residual myopic error with a mean spherical equivalent of -1.00 ± 0.69 D following myopic LASIK were evaluated. The retreatment procedures were performed after an average of 13.67 ± 1.15 months of primary LASIK using Schwind Amaris 500E excimer laser, with trans-PRK plate form. All patients underwent slit-lamp microscopy, manifest and cycloplegic refraction, Sirius 3D corneal analysis, merging Scheimpflug technology with Placido topography, pachymetry, pupillometry, and wavefront analysis preoperatively and postoperatively. All patients underwent follow-up on day 1, at 1 week, and at 1, 3, and 6 months. Results Mean time between LASIK and PRK retreatment was 19.2 months (range 13-39 months). No intraoperative or postoperative complications occurred during primary LASIK or trans-PRK retreatment. Mean spherical equivalent refraction of attempted correction with PRK was -1.58 D (range -0.50 to -2.25 D). By the end of sixth postoperative month, the average uncorrected visual acuity improved from 0.48 (range 0.15-0.7) to 0.7 (range 0.3-1.0). All eyes showed improvement in uncorrected visual acuity. Four eyes had subjective improvement of glare symptoms. None of the eyes in the cohort developed postoperative haze or any complications. Conclusion Trans-PRK with adjunctive MMC is a safe and effective option for correction of residual myopia following LASIK.


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